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KMID : 0363420180320040024
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Journal of Korean Oriental Pediatrics
2018 Volume.32 No. 4 p.24 ~ p.41
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Literature Review of Clinical Studies for Herbal Medicine Treatment on Juvenile Idiopathic Arthritis (JIA)
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Kim Mi-Yeon
Jeong Ju-Hui
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Abstract
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Objectives: The purpose of this study is to investigate the clinical studies on the effect of herbal medicine in JIA and to seek better approach of herbal medicine to treat JIA.
Methods: This study researched randomized controlled trials through various databases in the world about herbal medicine treatments in JIA.
Results: 11 out of 414 studies were selected and analyzed. All studies were conducted in China. Most of the studies were using herbal medicines, as an adjunctive treatment to the main regimen, and the total effective rate was higher in the treatment group than in the control group. One study was comparing the herbal oriental medicine treatment to the western medicine treatment, and it showed that treatment group was more effective than control group. 5 out of 11 studies reported treatment cases from a single herbal medicine; most of them used Total glucosides of Paeonia (TGP). Clematidis Radix et Rhizoma (威靈仙) were also commonly used, as well as medicinal herbs belong to Eliminating wind-dampness medicine (祛風濕藥) and Activating blood resolving stasis medicine (活血祛瘀藥).
Conclusions: Based on this study, herbal medicines for JIA treatment will be effective even if used alone or in conjunction with other medicines. To apply clinically, further studies are needed.
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KEYWORD
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Juvenile idiopathic arthritis, JIA, JRA, Herbal medicine, TCM
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